Tom Aharon Hait

PhD. Student in Bioinformatics
Blavatnik School of Computer Science, Sackler Faculty of Medicine, Tel Aviv University
Advised by Prof. Ron Shamir and Dr. Ran Elkon
Member of Algorithms in Computational Genomics and Elkon's Group

Research Interests

I work on developing computational methods for the analysis of multi-omics data in genome regulation.
  • Genome structure
  • Enhancer-promoter network inference
  • Non-coding regulatory elements prediction and function
  • Epigenomics and Transcriptomics

    • Tools

    CT-FOCS (Cell Type-specific Enhancer-Promoter database)

    FOCS (Enhancer-Promoter database)

    EXPANDER (EXpression Analyzer and DisplayER)

    EXPANDER in Russian

    Publications
    1. Tom Aharon Hait, Ran Elkon and Ron Shamir: CT-FOCS: a novel method for inferring cell-type specific enhancer-promoter maps. Nucleic Acids Res., 2022. PubMed
    2. I. Grigg, Y. Ivashko-Pachima*, T. A. Hait*, V. Korenková, O. Touloumi, R. Lagoudaki, A. Van Dijck, Z. Marusic, M. Anicic, J. Vukovic, R. F. Kooy, N. Grigoriadis & I. Gozes: Tauopathy in the young autistic brain: novel biomarker and therapeutic target. Translational Psychiatry (2020), Volume 10, Article number 228. *contributed equally. PubMed
    3. Tom Aharon Hait, Adi Maron-Katz, Dorit Sagir, David Amar, Igor Ulitsky, Chaim Linhart, Amos Tany, Roded Sharan, Yosef Shiloh, Ran Elkon, and Ron Shamir: The EXPANDER Integrated Platform for Transcriptome Analysis. J. Mol. Biol. (2019), Volume 431, Issue 13, Pages 2398-2406. PubMed
    4. Tom Aharon Hait, David Amar, Ron Shamir and Ran Elkon: FOCS: a novel method for analyzing enhancer and gene activity patterns infers an extensive enhancer-promoter map. Genome Biol 2018, 19:56. PubMed
    5. David Amar, Tom Hait, Shai Izraeli and Ron Shamir: Integrated analysis of numerous heterogeneous gene expression profiles for detecting robust disease-specific biomarkers and proposing drug targets. Nucleic Acids Research, 2015, Volume 43, Issue 16, pp. 7779–7789. PubMed

    Conference Talks
    1. Tom Aharon Hait, David Amar, Ron Shamir and Ran Elkon: "FOCS: a novel method for analyzing enhancer and gene activity patterns infers an extensive enhancer–promoter map". Seminar talk. Ronna Hertzano Laboratory, University of Maryland, Baltimore, Maryland, USA, May 9th 2019.
    2. Tom Aharon Hait, David Amar, Ron Shamir and Ran Elkon: "FOCS: a novel method for analyzing enhancer and gene activity patterns infers an extensive enhancer–promoter map". Highlight talk. In RECOMB 2019, The George Washington University, Washington DC, USA, 5-8 May 2019.
    3. Tom Aharon Hait, Ran Elkon and Ron Shamir: "CT-FOCS: a novel method for genome-wide inference of cell type-specific enhancer-promoter maps". Symposium talk. In Epigenetics, genome regulation and the impact on medicine, The Tel-Aviv University, Tel-Aviv, Israel, April 10th 2019.
    4. Tom Aharon Hait, David Amar, Ron Shamir and Ran Elkon: "Large-scale analysis of genome-wide enhancer and gene activity reveals a novel enhancer-promoter map". In Genome Informatics meeting, Cold Spring Harbor Laboratory, NY, USA, Nov 1-4 2017.

    Contact

    Email: tomhait[at]tauex[dot]tau[dot]ac[dot]il
    Address: 223/732 Schreiber/Sackler Buildings
    Blavatnik School of Computer Science
    Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine
    Tel Aviv University
    Tel Aviv 69978, Israel