(1) Biomedical Engineering Dept.; Tel Aviv University; Tel Aviv, 6997801; Israel. (2) The Sagol School of Neuroscience; Tel Aviv University; Tel Aviv, 6997801; Israel.
Nucleic Acids Research, 2017. DOI:10.1093/nar/gkx205
For an online interactive database of annotated conserved and divergent SCOMs between the budding yeast S. cerevisiae and the fission yeast S. pombe, see the NDEx site.
The following scripts require MATLAB (for generating conservation / divergence networks from Hi-C data) and python (for detecting SCOMs in given networks, tested on python 3). The provided shell script 'example.sh' demonstrates the pipeline for a small-scale example.