Large-scale mapping of human protein-protein interactions by mass spectrometry
ERK1b, a 46-kDa ERK isoform that is differentially regulated by MEK
Usherin, the defective protein in Usher syndrome type IIA, is likely to be a component of interstereocilia ankle links in the inner ear sensory cells
Myosin XVa and whirlin, two deafness gene products required for hair bundle growth, are located at the stereocilia tips and interact directly
Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2
Stereociliary myosin-1c receptors are sensitive to calcium chelation and absent from cadherin 23 mutant mice
Balanced levels of Espin are critical for stereociliary growth and length maintenance
Usher syndrome type I G (USH1G) is caused by mutations in the gene encoding SANS, a protein that associates with the USH1C protein, harmonin
Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C
Myosin VIIA is specifically associated with calmodulin and microtubule-associated protein-2B (MAP-2B)
A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration
Molecular mechanisms underlying cochlear degeneration in the tubby mouse and the therapeutic effect of sulforaphane
The unique insert in myosin VI is a structural calcium-calmodulin binding site
Vezatin, a novel transmembrane protein, bridges myosin VIIA to the cadherin-catenins complex
Mosaic complementation demonstrates a regulatory role for myosin VIIa in actin dynamics of stereocilia
Properties of MEKs, the kinases that phosphorylate and activate the extracellular signal-regulated kinases
Calmodulin in action: diversity in target recognition and activation mechanisms
Requirement for Map2k1 (Mek1) in extra-embryonic ectoderm during placentogenesis
Stress-induced inhibition of ERK1 and ERK2 by direct interaction with p38 MAP kinase
Glutathione-thiyl radical scavenging and transferase properties of human glutaredoxin (thioltransferase). Potential role in redox signal transduction
MAGI-1, a candidate stereociliary scaffolding protein, associates with the tip-link component cadherin 23
Myosin-XVa is required for tip localization of whirlin and differential elongation of hair-cell stereocilia
Characterization of ERK1 activation site mutants and the effect on recognition by MEK1 and MEK2
Glyceraldehyde-3-phosphate dehydrogenase regulates endothelin-1 expression by a novel, redox-sensitive mechanism involving mRNA stability
MAPK3/1 (ERK1/2) in ovarian granulosa cells are essential for female fertility
A human protein-protein interaction network: a resource for annotating the proteome
DOC-2/DAB2 is the binding partner of myosin VI
Stimulatory role of PKCalpha in extracellular regulated kinase 1/2 pathway in conjunctival goblet cell proliferation
IntAct--open source resource for molecular interaction data
ERK phosphorylates p66shcA on Ser36 and subsequently regulates p27kip1 expression via the Akt-FOXO3a pathway: implication of p27kip1 in cell response to oxidative stress
Myosin VI binds to and localises with Dab2, potentially linking receptor-mediated endocytosis and the actin cytoskeleton
Towards a proteome-scale map of the human protein-protein interaction network
Mechanism in the sequential control of cell morphology and S phase entry by epidermal growth factor involves distinct MEK/ERK activations
Myosin VI targeting to clathrin-coated structures and dimerization is mediated by binding to Disabled-2 and PtdIns(4,5)P2
Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells
Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning
Pathway of phosphatidylinositol(3,4,5)-trisphosphate synthesis in activated neutrophils
Interactions in the network of Usher syndrome type 1 proteins
Transient increase in phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol trisphosphate during activation of human neutrophils
Usher syndrome: animal models, retinal function of Usher proteins, and prospects for gene therapy
p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1
Human Ca2+/calmodulin-dependent protein kinase kinase beta gene encodes multiple isoforms that display distinct kinase activity
Propagation of the apoptotic signal by mitochondrial waves