SPIKE is a database of highly curated human signaling pathways with an associated interactive software tool.
Users can view and download individual pathway maps and browse the entire database from this website, or launch a map viewer tool that allows dynamic visualization of the database and save networks in XGMML format that can be viewed in all generic XGMML viewers.
Browsing and downloading the database does not require registration or login.
Users can view and download individual pathway maps and browse the entire database from this website, or launch a map viewer tool that allows dynamic visualization of the database and save networks in XGMML format that can be viewed in all generic XGMML viewers.
Browsing and downloading the database does not require registration or login.
Map Topics
- Cell cycle progress and check points
- DNA damage response
- Programmed cell death related processes
- Stress-activated transcription factors
- Mitogen-activated protein kinase pathways
- Immune response signaling
- HEarSpike: hearing related pathways