Spring 2005
Analysis of DNA Chips and Gene Networks

Course Requirements and Grading


The course has no class final exam - the grade is based on the following components:
 
1. Scribe

Each 2-3 students (the number depends on final course enrollment) will scribe (i.e., to prepare lecture notes for) one lecture. The notes should be prepared in LaTeX, and corrected according to guidelines and marks given by the TA and/or the instructor. Precise instructions and schedule are given here . Notes should contain all the material presented in class, written in clear and accurate fashion, as well as the relevant references.  Using figures and diagrams when necessary in order to clarify things is recommended. In most lectures, the scribes of lectures given in a previous year in the course can be used as a basis.

2. Literature Review Project
Students who will not be assigned a scribe task should do a literature review project instead. The project can be done in pairs. The subject of the project can be chosen from the list of topics covered in the course, or a related topic. Each pair is required to schedule a  meeting with the instructor/TA to obtain consent to the topic, discuss relevant papers and the direction for your project.

The project should include (i) a summary of the literature on this subject, (ii) a short summary of tools available, (iii) a clear description of the biological goal of the framework, (iv) a clear description of the computer science/mathematics tools used to solve the problem, (v) clear examples, (vi) a short summary of open computational problems in the area, (vii) either a small implementation of one of the algorithms/concepts in the paper with some experimentation or a theoretical investigation of a computational problem from one of the papers, and (viii) bibliography. 

Upon completion of the project, it will be presented in writing and also orally in a 15 minute meeting with the TA/instructor.

3. Theoretical Exercises
3-4 theoretical exercise sets will be given during the course. Solutions should be done independently by each student and without help from others. Use of books and articles for the solutions is allowed and will not affect the grading, but the sources should be noted in the solutions.  Most assignments contain built-in bonus, so by completing some 90% worth of all exercises you will be given full score.

4. Programming Project
Students will be assigned a project which will require writing code (implementing algorithms from the literature), applying it to public gene expression datasets and reporting the results. The project can be done in pairs.

Breakdown of final grade (tentative) :
1. Scribe / Literature Review: 25%
3. Theoretical Exercises: 50%

4. Programming Project: 25%

Tardiness:
Scribe preparation is done in two steps, each of which has its own deadline. Scribe grade will lose one point for each late day past each of the two deadlines. This is done in order to ensure that scribes are completed and made available to the whole group promptly.

Deadlines for theoretical exercises are strict - no late submission is allowed without prior authorization from the instructor /TA.

Projects should be handed in not later than June 10th. Late projects will lose one point for each late day.