DISCRETE APPLIED MATHEMATICS Announcing a Special Issue on Computational Molecular Biology Guest Editors: Sorin Istrail, Pavel Pevzner, Ron Shamir Submission Deadline: May 31, 1995 Manuscripts are solicited for a special issue of DISCRETE APPLIED MATHEMATICS on topics concerning the development of new combinatorial and algorithmic techniques in computational molecular biology. With this announcement "Discrete Applied Mathematics" starts a series of special issues devoted to computational biology. This series will publish papers on the mathematical and algorithmic foundations of the inherently discrete aspects of computational biology. The traditional partnership of mathematics and physics has advanced and enriched both disciplines. In a similar partnership, mathematics and algorithms are becoming crucial tools in the rapid advancement of molecular biology. At the same time, the computational challenges of these biological disciplines raise exciting new problems in discrete mathematics and theoretical computer science. To paraphrase Stan Ulam, those challenges reflect "not only what mathematics can do for biology but what biology can do for mathematics." The following is a (nonexhaustive) list of possible topics of interest for the special issue: - DNA mapping - DNA sequencing - DNA/protein sequence comparison - molecular evolution - RNA/protein structure - gene/motif recognition Seven (7) copies of complete manuscripts should be sent to any of the Guest Editors indicated below by May 31, 1995. We expect the Special Issue to appear in the Fall 1996. Manuscripts must be prepared according to the normal submission requirements of Discrete Applied Mathematics, as described in each issue of the journal. The Guest Editors will make every possible effort to assure the timely completion of a thorough refereeing process. The Guest Editors are: Sorin Istrail Sandia National Laboratories Algorithms and Discrete Mathematics Department MS 1110 Albuquerque, NM 87185-1110 scistra@cs.sandia.gov Pavel Pevzner Dept. of Computer Science and Engineering The Pennsylvania State University University Park, PA 16802 pevzner@cse.psu.edu Ron Shamir Dept. of Computer Science Tel Aviv University Tel Aviv 69978 ISRAEL shamir@math.tau.ac.il