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DNA replication

The genetic information embodied in DNA can be replicated into more DNA. When DNA is replicated, its two strands are split and each strand serves as a template for a new forming strand: Each base in the template dictates the complementary base in the new strand. The replication reaction is catalyzed by the enzyme DNA polymerase. This enzyme can extend a chain, but cannot start a new one. Therefore, DNA synthesis must first be initiated with a primer, a short oligonucleotide (nucleotide chain). The oligonucleotide generates a segment of duplex DNA that is then turned into a new strand by the replication process (see figure 1.1).

  
Figure: DNA [4]

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Peer Itsik
2000-11-13