Data Mining for Enzymes Search Utility - DME11

Active, Metal and Binding Site Annotations, as well as gene names and domain attributions
are based on Specific Peptides (SPs) extracted from Swissprot Data


Specific PeptideECFunctionLocation of SP in ProteinPredicted Features
LFVALYD2.7.10.2;Non-specific protein-tyrosine kinase. 65
  • Domain: SH3
NSLEKHSWYHGP2.7.10.2;Non-specific protein-tyrosine kinase. 120
  • Domain: SH3
INGSFLVRESESSPGQ2.7.10.2;Non-specific protein-tyrosine kinase. 145
  • Domain: SH2
ELVHHHS2.7.10.2;Non-specific protein-tyrosine kinase. 197
  • Domain: SH2
TTLHYPAPK2.7.10.2;Non-specific protein-tyrosine kinase. 211
  • Domain: SH2
KLGGGQYG2.7.10.2;Non-specific protein-tyrosine kinase. 247
  • Domain: Protein kinase
GVWKKYSLTVAVKT2.7.10.2;Non-specific protein-tyrosine kinase. 259
  • Binding Site K=Lysine at location 271 on the protein
  • Binding site description: ATP (By similarity).
  • Domain: Protein kinase
KEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCT2.7.10.2;Non-specific protein-tyrosine kinase. 274
  • Domain: Protein kinase
GVCTREPPFYIITEFM2.7.10.2;Non-specific protein-tyrosine kinase. 303
  • Domain: Protein kinase
YGNLLDYLREC2.7.10.2;Non-specific protein-tyrosine kinase. 320
  • Domain: Protein kinase
LLYMATQI2.7.10.2;Non-specific protein-tyrosine kinase. 340
  • Domain: Protein kinase
RDLAARN2.7.10;Protein-tyrosine kinases. 362
  • Active Site D=Aspartic acid at location 363 on the protein
  • Active Site Description: Proton acceptor (By similarity
  • Domain: Protein kinase
KFPIKWTAPE2.7.10.2;Non-specific protein-tyrosine kinase. 400
  • Domain: Protein kinase
LAYNKFS2.7.10.2;Non-specific protein-tyrosine kinase. 411
  • Domain: Protein kinase
KSDVWAFGVLLWEIATYGM2.7.10.2;Non-specific protein-tyrosine kinase. 419
  • Domain: Protein kinase
KVYELMRACW2.7.10.2;Non-specific protein-tyrosine kinase. 467
  • Domain: Protein kinase
HQAFETMF2.7.10.2;Non-specific protein-tyrosine kinase. 490
  • Domain: Protein kinase
PLRRQVTV2.7.10;Protein-tyrosine kinases. 817 -
RNKFAFREA2.7.10.2;Non-specific protein-tyrosine kinase. 1078 -

Mapping of the Specific Peptides in the Protein

Red characters denote the location of the Specific Peptide Matches


---------+---------+---------+---------+---------+---------+---------+---------+---------+---------+
MLEICLKLVGCKSKKGLSSSSSCYLEEALQRPVASDFEPQGLSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWC
EAQTKNGQGWVPSNYITPV
NSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVH
HHS
TVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQ
LLGVCTREPPFYIITEFM
TYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAK
FPIKWTAPE
SLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQES
SISDEVEKELGKQGVRGAVSTLLQAPELPTKTRTSRRAAEHRDTTDVPEMPHSKGQGESDPLDHEPAVSPLLPRKERGPPEGGLNEDERLLPKDKKTNLF
SALIKKKKKTAPTPPKRSSSFREMDGQPERRGAGEEEGRDISNGALAFTPLDTADPAKSPKPSNGAGVPNGALRESGGSGFRSPHLWKKSSTLTSSRLAT
GEEEGGGSSSKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRAGENRSDQVTRGTVTPPPRLVKKNEEAADEVFKD
IMESSPGSSPPNLTPK
PLRRQVTVAPASGLPHKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSESPGRDKGKLSRLKPAPP
PPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNSDAAKPSQPGEGLKKPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPSST
AFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQM
RNKFAFREAINKLENNLRELQIC
PATAGSGPAATQDFSKLLSSVKEISDIVQR



DME EC Prediction for this protein is: 2.7.10.2
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